First off I'd suggets you go with at least a 78mm stroke. The cost difference is nill and it's actually easier to do. Using either a 74 or 76 stroke crank will force you to use 'A' pistons which means large spacer. That in turn means a wide engine,, which means exhaust fits funny, tins fit funny,, everything is gonna need work above and beyond a 'normal' build.
Next, you really want a new case when you're thinking of a performance build. The only alternaitive is if you know the entire history of your current case and it's been throughly looked over. For example, I just recently had to junk a case that bought new a few years ago, it was just too far gone to put back into service.
Cam, I'd recommend against a stock cam in a stroker, you will absolutely hate the power band, it'll be over sooner than a stock engine. The stroker wants more air (displacement) yet you're still providing it with the same amount as you would a stock engine by using a stock cam. With that comes carbs, duals are the way to go here. With a mild cam like an Engle 110 (min, I'd actually say a 120 or k8) you could go with dual 40s. With a larger cam then 44s are a good choice, 48s if you really want to open it up.
Compression ratio depends on way too many things. Pick a cam, heads, level of port work, carbs, exhaust, etc, and then think about compression ratios.
On the other hand, if you're just looking for a good solid reliable fun to drive, easy to build, low maintanance engine. It's hard to beat a 1776 with a 110 cam and dual carbs and a 1 1/2" merged header. Set the compression to 8.0 and you'll be happy. -Ryan